Benefits
Bio-Stimulating Polynucleotide Formula
ICONA® Pn+ Face delivers 40mg/ml polynucleotides and 20mg/ml HA in a balanced formulation optimised for facial dermis. It promotes fibroblast activity and collagen renewal without volume — ideal for restoring tone and radiance across full-face zones.
R³ Regenerative Support
Driven by R³ Technology™, Pn+ Face initiates a three-phase regenerative cycle: Repair (cell activation), Restore (collagen and elastin), and Reinforce (hydration and ECM strength). The result is visibly improved facial skin texture and elasticity.
Natural Glow, No Puffiness
Non-crosslinked and lidocaine-free, Pn+ Face hydrates deeply without disrupting facial contours. Skin appears smoother, more supple, and luminous — with results that enhance natural features rather than change them.
Multi-Zone Polynucleotide Formulas
Each ICONA® Pn+ product is precisely formulated for its treatment zone — face, body, eyes, or scalp. With targeted concentrations of polynucleotides and co-factors, the range offers medical professionals a regenerative solution tailored to specific anatomical needs.
R³ Regenerative Technology
Powered by R³ Technology™, ICONA® Pn+ supports controlled tissue repair across all indications. This structured 3-phase system — Repair, Restore, Reinforce — helps regenerate dermal structure, improve elasticity, and optimise the extracellular environment.
Natural, Non-Volumising Outcomes
Designed for subtle yet clinically meaningful results, ICONA® Pn+ improves skin texture, hydration, and density without adding volume. Patients experience visible quality improvements with minimal downtime — ideal for high-demand, natural-look rejuvenation.
Features
Polynucleotides (40mg/ml)
High-strength polydeoxyribonucleotide chains that stimulate fibroblasts, support tissue regeneration, and improve extracellular matrix integrity for visible dermal renewal.
Hyaluronic Acid (20mg/ml)
Non-crosslinked, ultra-pure HA provides deep hydration and matrix support — boosting elasticity and plumpness without altering facial structure.
R³ Technology™
A proprietary 3-phase regenerative mechanism:
• Repair — Cellular activation
• Restore — Collagen and elastin support
• Reinforce — ECM hydration and resilience
Why Choose
Improved Skin Density and Structure
Tissue appears stronger, more compact, and visibly firmer — reflecting improved ECM integrity and fibroblast activity.
Natural-Looking Rejuvenation
Restores skin quality without volume or puffiness. Results are subtle, progressive, and designed to enhance—not alter—facial identity.
Refined Texture and Tone
Surface becomes noticeably smoother and more uniform, with reduced roughness, fine lines, and early creping.
Hydrated, Balanced Skin Appearance
Skin feels more hydrated and resilient, with reduced dryness and improved barrier function from the inside out.
How It Works
ICONA® Pn+ injectables are delivered via precise micro-injections into targeted dermal planes based on the treatment zone — including facial, body, periocular, and scalp applications. This strategic protocol ensures optimal absorption of active ingredients while minimising downtime and inflammation.
Using micro-bolus or mesotherapy techniques depending on indication, the polynucleotide-based solution is introduced into the extracellular matrix. Once there, it stimulates fibroblast proliferation, enhances collagen and elastin synthesis, supports angiogenesis, and improves tissue hydration — all without altering volume or facial structure.
