The ICONA PN Polynucleotide range represents the latest advancement in regenerative aesthetic treatments, designed to support deep skin repair and long-lasting rejuvenation. Developed by Icona UK, this innovative collection harnesses the power of polynucleotides to improve skin quality, enhance hydration, and promote a healthier, more radiant complexion. By working at a cellular level, the range helps to restore skin structure, boost elasticity, and reduce visible signs of ageing. Suitable for a variety of treatment areas, the Icona PN range is quickly becoming a preferred choice for professionals seeking effective, science-led solutions for natural-looking skin revitalisation.

  • CE certified
  • Precisely formulated for its intended treatment zone
  • Designed to improve overall skin quality by targeting damage at a cellular level

Benefits ICONA Polynucleotides

Multi zone Polynucleotide formulas

Each ICONA® Pn product is precisely formulated for its intended treatment zone — face, body, eyes, or scalp. With targeted concentrations of polynucleotides and specialised co-factors, the range provides medical professionals with a versatile bio-stimulatory solution tailored to the differing structural and aesthetic requirements of each anatomical area.

R³ REGENERATIVE TECHNOLOGY™

Powered by R³ Technology™, ICONA® Pn is designed to support tissue quality improvement across multiple indications. This structured three-phase framework — Repair, Restore, Reinforce — reflects a formulation philosophy focused on supporting dermal structure, enhancing elasticity, and optimising the extracellular environment over time.

NATURAL, NON-VOLUMISING OUTCOMES

Designed for subtle yet clinically meaningful aesthetic improvement, ICONA® Pn supports improvements in skin texture, hydration, and overall skin quality without adding volume or altering facial structure. Patients may experience visible enhancements with minimal downtime, making the range well suited to natural-look rejuvenation protocols.

How it works

Targeted dermal placement supporting bio-stimulating skin quality improvement across multiple anatomical zones

ICONA® Pn injectables are administered via precise micro-injection techniques into targeted dermal planes, selected according to the treatment area — including facial, body, periocular, and scalp applications. This controlled placement approach is designed to optimise local dermal availability while supporting tissue tolerance and minimising procedural downtime.

Depending on clinical indication, micro-bolus or mesotherapy techniques may be employed to introduce the polynucleotide-based formulation into the extracellular matrix. Within the dermal environment, the formulation is designed to support fibroblast-associated activity, contribute to collagen- and elastin-related structural processes, assist in maintaining dermal hydration, and promote a tissue environment associated with long-term skin quality improvement — without altering volume or facial structure.

The Result

Visible outcomes and proven effectiveness 

  • Improved Skin Density and Structure
    Tissue appears stronger, more compact, and visibly firmer — reflecting improved ECM integrity and fibroblast activity.
  • Natural-Looking Rejuvenation
    Restores skin quality without volume or puffiness. Results are subtle, progressive, and designed to enhance—not alter—facial identity.
  • Refined Texture and Tone
    Surface becomes noticeably smoother and more uniform, with reduced roughness, fine lines, and early creping.
  • Hydrated, Balanced Skin Appearance
    Skin feels more hydrated and resilient, with reduced dryness and improved barrier function from the inside out.

ICONA Polynucleotide range

ICONA H8 special offers